NCT00702117

Ajmaline Utilization in the Diagnosis and Treatment of Cardiac Arrhythmias

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 123 (actual)
• Sponsor: Hospital Clinic of Barcelona · Academic / Other
• Sex: All
• Age: 10 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The study evaluates 3 different populations: It is an open, randomized, parallel-group study comparing the effectiveness of intravenous (iv) ajmaline with currently used antiarrhythmic drugs in the acute treatment of : 1. recent-onset atrial fibrillation versus iv flecainide 2. sustained monomorphous ventricular tachycardia versus iv procainamide The study also evaluates in an open, randomized, crossover study, the use of iv ajmaline versus iv flecainide in the diagnosis of Brugada syndrome

Conditions

• Atrial Fibrillation
• Tachycardia, Ventricular
• Brugada Syndrome

Interventions

Type	Name	Description
DRUG	flecainide	2 mg/kg iv in 10 minutes
DRUG	ajmaline	1 mg/kg iv in 10 minutes
DRUG	procainamide	10 mg/kg iv in 10 minutes

Timeline

• Start date: 2008-06-01
• Primary completion: 2010-01-01
• Completion: 2010-01-01
• First posted: 2008-06-20
• Last updated: 2010-12-15

Locations

4 sites across 1 country: Spain