NCT00701623

Sodic Heparin Effectiveness of the Treatment of Burns

Clinical Efficacy of Product Alimax ® (Sodic Heparin) in Treatment of Burns: Comparative Study of Raw Materials Between Two Suppliers

• Status: Withdrawn
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Azidus Brasil · Industry
• Sex: All
• Age: 12 Years
• Healthy volunteers: Accepted

Summary

Burns are injuries caused by agents thermal, chemical, electrical or radioactive who act in the tissue lining of the human body and may partially or totally destroy the skin and its annexes, to the deeper layers, as subcutaneous tissue, muscles, tendons and bones . Studies show that topical heparin has, in addition to the already known anticoagulant activity, anti-inflammatory properties, analgesic, and neoangiogenic, stimulating blood flow and increasing the repair of the fabric as well as the restoration of collagen and reepiteliztion. Moreover, the use of heparin reduces the need for painful medical procedures, as debridations, surgeries and transplants The intention of this work is to verify the effectiveness and safety of sodium heparin in the treatment of burns of the skin.

Detailed description

Patients with burns that come to the emergency room will be informed about the Inclusion Criteria * Patients aged above 12 years who have suffered thermal burns of 2nd degree burns or mixed 2 and 3 degrees in up to 10% of body surface and indication of outpatient treatment. Exclusion Criteria * Area burned more than 10% of body surface * the presence of the 3 rd degree burns * burns in the face or genitals * burns in poly-traumatized * respiratory injury * disorders of coagulation * thrombocytopenia * erosive gastro cases * clinically relevant bleeding * hypersensitivity to anticoagulants * liver disease * nephropathy * diabetes * 35 * serious allergy * descontrole emotional * pregnancy * anemia

Conditions

• Burns

Interventions

Type	Name	Description
DRUG	heparin	patients will receive the application of one of two types of heparin directly on the injured area
DRUG	heparin	patients will receive the application of one of two types of heparin directly on the injured area
DRUG	folder water	patients will receive the application of folder water directly on the injured area

Timeline

• Start date: 2008-06-01
• Primary completion: 2008-06-01
• Completion: 2008-06-01
• First posted: 2008-06-19
• Last updated: 2022-11-03

Locations

1 site across 1 country: Brazil