NCT00700375

Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate Bolus Injection

Prevention of Contrast-Induced Nephropathy With Sodium Bicarbonate Bolus Injection in Patients Undergoing an Emergent Coronary Procedure

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 59 (actual)
• Sponsor: Osaka General Medical Center · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

This study is to investigate the effect of Sodium Bicarbonate bolus injection in patients undergoing an emergent coronary procedure for prevention of contrast-induced nephropathy.

Detailed description

This study is to investigate the effect of Sodium Bicarbonate bolus injection in patients undergoing an emergent coronary procedure for prevention of contrast-induced nephropathy.The End point is development of contrast-induced nephropathy.

Conditions

• Emergent Coronary Procedure

Interventions

Type	Name	Description
DRUG	Sodium bicarbonate	8.4%sodium bicarbonate 0.5ml/kg bolus injection before procedure and hydration with 154mEq/l sodium bicarbonate 1ml/kg/Hr for 6 hours after the procedure
DRUG	Sodium Chloride	8.4%sodium bicarbonate 0.5ml/kg bolus injection before procedure and hydration with 154mEq/l sodium bicarbonate 1ml/kg/Hr for 6 hours after the procedure

Timeline

• Start date: 2008-07-01
• Primary completion: 2010-03-01
• Completion: 2010-03-01
• First posted: 2008-06-18
• Last updated: 2010-07-20
• Results posted: 2010-07-09

Locations

1 site across 1 country: Japan