NCT00699621

Platelet Transfusion in Acute Intracerebral Hemorrhage

Platelet Transfusion in Acute Primary Intracerebral Hemorrhage for Patients on Platelet Inhibitors

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: University of Oulu · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

* To prove whether use of antiplatelet agents results into a rapid enlargement of hematoma after onset of acute intracerebral hemorrhage. * To prove the efficacy and safety of platelet transfusion for prevention of hematoma growth in patients who were stricken by acute intracerebral hemorrhage while being on antiplatelet medication.

Detailed description

* Hematoma growth is a well-known powerful determinant of mortality and poor outcome after intracerebral hemorrhage. * Some observations suggest that previous use of antiplatelet agents associates with rapid hematoma enlargement and poor outcome after cerebral hemorrhage. * Immediate platelet transfusion for such patients may prevent hematoma growth but also cause thromboembolic complications.

Conditions

• Intracerebral Hemorrhage

Interventions

Type	Name	Description
BIOLOGICAL	platelets	Four units of fresh platelets will be infused immediately

Timeline

• Start date: 2009-01-01
• Primary completion: 2014-07-01
• Completion: 2014-12-01
• First posted: 2008-06-18
• Last updated: 2010-07-02

Locations

1 site across 1 country: Finland