NCT00699556

Do Treatments for Smoking Cessation Affect Alcohol Drinking? Study 1: Nicotine Replacement Therapy

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

This study examines the effect of combined nicotine replacement therapy (transdermal patch + nasal spray vs. transdermal patch + placebo nasal spray) on reactivity to alcohol and self-administration behavior.

Conditions

• Alcohol Drinking

Interventions

Type	Name	Description
DRUG	21mg transdermal nicotine patch (Nicoderm CQ)	21mg transdermal nicotine patch
DRUG	1mg nicotine nasal spray	two 0.5mg/sprays, one to each nostril (dose = 1mg) The nicotine nasal spray is formulated by the Investigational Drug Service at Yale-New Haven Hospital. It is similar in concentration to Nicotrol.
DRUG	placebo nasal spray	saline combined with capsaicin to mimic the brief nasal irritation from active nicotine spray The placebo nasal spray is formulated by the Investigational Drug Service at Yale-New Haven Hospital.

Timeline

• Start date: 2006-01-01
• Primary completion: 2016-11-01
• Completion: 2016-11-01
• First posted: 2008-06-18
• Last updated: 2018-03-12
• Results posted: 2018-03-12

Locations

1 site across 1 country: United States