NCT00695461

Lactobacillus Plantarum 299v in Colon Surgery

L Plantarum 299v to Patients Undergoing Colon Resection - a Randomized Placebo-Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: Skane University Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Intestinal pathogenes are often involved in postoperative complications after colon surgery. Probiotic bacteria, i e live bacteria which have beneficial effects on the host when ingested, have been shown to reduce bacterial translocation in animal studies. However, in humans studies results have varied. The purpose with this study was to find whether high doses of Lactobacillus plantarum 299v affects the potentially pathogenic microflora of the gut, bacterial translocation and cell proliferation in patients undergoing planned colon surgery.

Conditions

• Bacterial Translocation
• Inflammation
• Cell Proliferation

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Lactobacillus plantarum 299v in oatmeal drink	Bacteria in a concentration of 10(9) CFU/ml
DIETARY_SUPPLEMENT	Oatmeal drink	Oatmeal drink as in arm 1 but without bacteria added.

Timeline

• Start date: 2001-01-01
• Primary completion: 2004-06-01
• Completion: 2006-08-01
• First posted: 2008-06-11
• Last updated: 2008-06-11

Locations

1 site across 1 country: Sweden