Clinical Trials Directory

Trials / Terminated

TerminatedNCT00695448

Phase I Open-Label, Dose-Escalation Study of GSK1059615 in Patients With Solid Tumors or Lymphoma

A Phase I Open-Label, Dose-Escalation Study of the Phosphoinositide 3-Kinase Inhibitor GSK1059615 in Patients With Solid Tumors or Lymphoma

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
11 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is an open-label, multi-center Phase I study conducted to define the recommended Phase 2 dose, toxicity profile, pharmacokinetics and biologically active dose range of GSK1059615.

Conditions

Interventions

TypeNameDescription
DRUGGSK1059615GSK1059615 is dosed orally once daily for 21 days of a 28-day cycle. Patients continue treatment for subsequent cycles as long as eligible and receiving benefit.

Timeline

Start date
2008-06-24
Primary completion
2009-03-31
Completion
2009-03-31
First posted
2008-06-11
Last updated
2017-07-25

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00695448. Inclusion in this directory is not an endorsement.

Phase I Open-Label, Dose-Escalation Study of GSK1059615 in Patients With Solid Tumors or Lymphoma (NCT00695448) · Clinical Trials Directory