Clinical Trials Directory

Trials / Terminated

TerminatedNCT00694967

A Randomized Trial of Cerclage Versus 17 α-Hydroxyprogesterone Caproate for Treatment of a Short Cervix

Histologic Evaluation of the Cervix at Risk for Preterm Birth Trial:Medical Versus Surgical Therapy

Status
Terminated
Phase
N/A
Study type
Interventional
Enrollment
92 (actual)
Sponsor
Lehigh Valley Hospital · Academic / Other
Sex
Female
Age
Healthy volunteers
Accepted

Summary

We hypothesized that weekly intramuscular injections of 17 hydroxyprogesterone caproate(17P) will reduce the number spontaneous preterm births prior to 35 weeks gestation when compared to cerclage therapy. The purpose of this study was to compare medical therapy with 17P to surgical therapy with transvaginal cerclage in patients with an ultrasound diagnosed short cervix and funnel in the mid-trimester.

Conditions

Interventions

TypeNameDescription
PROCEDUREMcDonald cerclage placementTranscervical McDonald cerclage placement
DRUG17 hydroxyprogesterone caproateWeekly 250mg intramuscular injections

Timeline

Start date
2003-11-01
Primary completion
2006-12-01
Completion
2006-12-01
First posted
2008-06-11
Last updated
2008-06-11

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00694967. Inclusion in this directory is not an endorsement.