NCT00694369

A Study to Asses the Effect of MK0663 in the Treatment of Patients With Postoperative Dental Pain (0663-092)

A Phase III Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled Multiple-Dose Clinical Trial to Study the Efficacy and Safety of MK0663/Etoricoxib 90 and 120 mg, Ibuprofen 600 mg, and Acetaminophen 600 mg/Codeine 60 mg in the Treatment of Patients With Postoperative Dental Pain

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 588 (actual)
• Sponsor: Organon and Co · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the pain relieving effect of different doses of MK0663 with placebo and other pain relievers/analgesics in patients with postoperative dental pain. Pain intensity and relief will be measured by the total pain relief score (TOPAR) and patient evaluation.

Conditions

• Postoperative Dental Pain

Interventions

Type	Name	Description
DRUG	Comparator: etoricoxib	etoricoxib 90 mg; 120 mg (once daily) over three days.
DRUG	Comparator: ibuprofen	ibuprofen 2400 mg (600 mg Q6h) over three Days
DRUG	Comparator: acetaminophen + codeine	acetaminophen 2400 mg/codeine 240 mg (600/60 mg Q6h) over three Days
DRUG	Comparator: placebo	matching placebo over three Days

Timeline

• Start date: 2008-06-01
• Primary completion: 2008-12-01
• Completion: 2009-01-01
• First posted: 2008-06-10
• Last updated: 2022-02-09
• Results posted: 2010-01-29