NCT00692536

Diet Composition - Metabolic Regulation and Long-term Compliance

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Umeå University · Academic / Other
• Sex: Female
• Age: 70 Years
• Healthy volunteers: Accepted

Summary

This study will compare a high-protein/low-carbohydrate diet (modified paleolithic diet, MPD) with a diet high in slow carbohydrates (Nordic Nutrition Recommendations, NNR). The diets will be compared with respect effects on weight reduction, metabolic regulation, and long-term compliance to the diet regimes. Seventy-two postmenopausal overweight healthy women have been recruited and will be followed for two years. The following variables will be studied: * Anthropometry * DEXA * OGTT * Liver fat content measured with 1H-MRS * Hepatic 11β-HSD1 activity, measured with cortisone/cortisol conversion test

Conditions

• Obesity

Interventions

Type	Name	Description
BEHAVIORAL	NNR (Nordic Nutrition Recommendations)	Diet with equal amounts of fat, protein and carbohydrates
BEHAVIORAL	MPD (Modified paleolithic diet)	A diet high in protein and fat, but low in carbohydrates

Timeline

• Start date: 2007-09-01
• Primary completion: 2010-06-01
• Completion: 2010-06-01
• First posted: 2008-06-06
• Last updated: 2015-09-03

Locations

1 site across 1 country: Sweden