Trials / Completed
CompletedNCT00691067
A Controlled Trial of Mifepristone in Gulf War Veterans With Chronic Multisymptom Illness
A Randomized, Double-blind Placebo-controlled Crossover Trial of Mifepristone in Gulf War Veterans With Chronic Multisymptom Illness
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 65 (actual)
- Sponsor
- Bronx Veterans Medical Research Foundation, Inc · Academic / Other
- Sex
- All
- Age
- 35 Years
- Healthy volunteers
- Not accepted
Summary
We propose to conduct placebo-controlled trial of the glucocorticoid receptor antagonist mifepristone in Gulf War veterans (GWV) with chronic multisymptom illness (CMI) to examine its effects on physical and mental health and cognitive functioning. In addition, we propose to examine whether HPA axis biomarkers or their response to mifepristone are useful predictors of clinical response.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | mifepristone | 200 mg po per day x 6 weeks |
| DRUG | Placebos | placebo |
Timeline
- Start date
- 2008-05-01
- Primary completion
- 2012-08-01
- Completion
- 2012-08-01
- First posted
- 2008-06-05
- Last updated
- 2017-01-31
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00691067. Inclusion in this directory is not an endorsement.