NCT00690222

Intracameral Mydriasis Versus Topical Mydriasis in Cataract Surgery

A Comparison of Intracameral Phenylephrine 2% and Tropicamide 0.2% With Topical Phenylephrine 2.5% and Tropicamide 1% for Pupillary Dilation During Cataract Surgery on Patients With and Without Pseudoexfoliation Syndrome.

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Nova Scotia Health Authority · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose is to determine if an intracameral solution of 0.2% tropicamide and 2% phenylephrine can dilate the pupil for cataract surgery as well as pre-operative topical 1% tropicamide and 5% phenylephrine. We will be looking at two separate groups of patients, those with and those without pseudoexfoliation syndrome. We will be looking at how each method affects the size of the pupil at the beginning and at the end of cataract surgery. In addittion, we will look at what effect the two different methods have on blood pressure and heart rate in the pre-operative, peri-operative and post-operative periods.

Conditions

• Cataract
• Phacoemulsification
• Mydriasis
• Pseudoexfoliation Syndrome

Interventions

Type	Name	Description
PROCEDURE	Intracameral injection of mydriatic agent	A mixture of 0.2 % tropicamide and 2% phenylephrine will be injected into the anterior chamber at the beginning of surgery

Timeline

• Start date: 2008-03-01
• Primary completion: 2012-06-01
• Completion: 2012-06-01
• First posted: 2008-06-04
• Last updated: 2015-03-25

Locations

1 site across 1 country: Canada