Trials / Unknown
UnknownNCT00688389
Investigation of the Immuno-regulation and Viral Hepatitis Among Patients With or After Dengue Fever Infection
Follow-up the Health Condition , Investigation of the Immuno-regulation , and the Study for Interaction of Viral Hepatitis--- Among Patients With or After Dengue Fever Infection
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 700 (estimated)
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Accepted
Summary
The study will collect the blood samples from 350 healthy persons and 350 persons infected with dengue fever.
Detailed description
Research has showed that CLEC5A interacts with dengue virion directly, and is responsible for dengue virus (DV)-induced DAP12 phosphorylation. Data suggests that CLEC5A is a potential therapeutic target for dengue hemorrhagic fever (DHF)/dengue shock syndrome (DSS). This project will study the genes of CLEC5A, Mannose receptor, DC-SIGN, NALP, decoy receptor 3 (DcR3), Toll-like receptors(TLRs), and (Nod)-like receptors (NLRs) for both DF and DHF groups. In addition, serum level of decoy receptor 3 (DcR3) will be tested. The study will collect the blood samples from 350 healthy persons and 350 persons infected with dengue fever.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | case/control | case: infected dengue fever people control:healthy people |
Timeline
- Start date
- 2007-07-01
- Primary completion
- 2020-12-31
- Completion
- 2020-12-31
- First posted
- 2008-06-02
- Last updated
- 2019-02-28
Locations
1 site across 1 country: Taiwan
Source: ClinicalTrials.gov record NCT00688389. Inclusion in this directory is not an endorsement.