NCT00687986

Trial of Either Surgery or Stereotactic Radiotherapy for Early Stage (IA) Lung Cancer

A Randomized Clinical Trial of Surgery Versus Radiosurgery (Stereotactic Radiotherapy) in Patients With Stage IA NSCLC Who Are Fit to Undergo Primary Resection

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Amsterdam UMC, location VUmc · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The standard treatment for an early stage I lung cancer is surgery. However, surgery can be associated with complications and long-term impairment of the quality of life of patients. Stereotactic radiotherapy (SRT) is a outpatient technique which allows for local control rates that are comparable to those achieved using surgery. In this study, patients with stage IA non-small cell lung cancer will be randomized to either surgery or SRT in order to study the local and regional tumor control, quality of life and treatment costs at 2- and 5-years.

Conditions

• Lung Cancer

Interventions

Type	Name	Description
RADIATION	stereotactic radiotherapy	Either 3 fractions of 20 Gray or 5 fractions of 12 Gy
PROCEDURE	primary surgery	an anatomical surgical resection with lymph node dissection

Timeline

• Start date: 2008-10-01
• Primary completion: 2010-02-01
• Completion: 2010-02-01
• First posted: 2008-06-02
• Last updated: 2022-03-17

Locations

1 site across 1 country: Netherlands