Clinical Trials Directory

Trials / Approved For Marketing

Approved For MarketingNCT00686621

Single Patient Treatment of Posaconazole in Invasive Fungal Infections (Study P05113)

Single Patient Emergency Treatment Use of Posaconazole in Invasive Fungal Infections

Status
Approved For Marketing
Phase
Study type
Expanded Access
Enrollment
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
2 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to provide posaconazole compassionate treatment to patients with invasive fungal infections: 1) which are resistant to standard antifungal therapies; 2) for which there are no effective therapies; 3) with a prior history of serious, severe, or life-threatening toxicities while receiving standard antifungal therapies, or 4) with pre-existing organ dysfunction which precludes the use of standard antifungal therapies.

Detailed description

NCT00686621 was voluntarily registered even though it is a single patient use study, also known as compassionate exemption study; therefore results will not be disclosed for this study.

Conditions

Interventions

TypeNameDescription
DRUGPosaconazolePosaconazole oral suspension 400 mg twice daily with meal or nutritional supplement. Alternatively, if meal or nutritional supplement is not tolerated, posaconazole should be administered at a dose of 200 mg four times a day.

Timeline

First posted
2008-05-30
Last updated
2018-12-03

Source: ClinicalTrials.gov record NCT00686621. Inclusion in this directory is not an endorsement.