NCT00685191

HIV-1 Viral Dynamics in Subjects Initiating Raltegravir Therapy in Spain

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: Germans Trias i Pujol Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study purpose is to investigate plasma HIV-1 RNA dynamics in subjects initiating raltegravir-based salvage therapy and quantify the corresponding changes in levels of cellular HIV-1 DNA.

Detailed description

First- and second-phase decay rates of plasma HIV-1 RNA and changes in the intracellular levels of HIV-1 proviral DNA and LTR circles will be measured in subjects starting salvage antiretroviral therapy including raltegravir in Spain.

Conditions

• HIV Infections

Interventions

Type	Name	Description
DRUG	Salvage antiretroviral therapy including raltegravir	Initiation of raltegravir-including salvage antiretroviral therapy

Timeline

• Start date: 2008-06-01
• Primary completion: 2009-04-01
• Completion: 2009-10-01
• First posted: 2008-05-28
• Last updated: 2019-12-04

Locations

1 site across 1 country: Spain