Clinical Trials Directory

Trials / Completed

CompletedNCT00684645

Non-Interventional Study (NIS) In Patients With Advanced And/Or Metastatic Renal Cell Carcinoma (mRCC) Treated With SUTENT®

Non-Interventional Study In Patients With Advanced And/Or Metastatic Renal Cell Carcinoma (mRCC) Treated With SUTENT®

Status
Completed
Phase
Study type
Observational
Enrollment
186 (actual)
Sponsor
Pfizer · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Primary objective: to increase knowledge about safety, tolerability, quality of life and efficacy under conditions of routine use of SUTENT®. Secondary objectives: treatment response, hypothyroidism prevalence.The efficacy will be assessed using the Objective Response Rate, Time to Progression based on the RECIST criteria and the ECOG performance data.

Detailed description

180 patients will be enrolled at 20 key oncological centres, the sample size is sufficient for exploratory analysis.

Conditions

Interventions

TypeNameDescription
DRUGSUTENTSUTENT® hard gelatin capsules containing 12.5 mg, 25 mg or 50 mg equivalent of sunitinib malate; daily dosage of 50 mg for 4 consecutive weeks followed by a 2-week rest period. Sutent is administered until disease progression or occurrence of unacceptable toxicity.

Timeline

Start date
2008-06-01
Primary completion
2011-04-01
Completion
2011-04-01
First posted
2008-05-26
Last updated
2012-08-21
Results posted
2012-08-21

Locations

20 sites across 1 country: Czechia

Source: ClinicalTrials.gov record NCT00684645. Inclusion in this directory is not an endorsement.