NCT00683644

Zinc to Treat Tinnitus in the Elderly

Zinc to Treat Tinnitus in the Elderly: A Randomized Placebo Controlled Crossover Trial.

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 116 (actual)
• Sponsor: University of Iowa · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Not accepted

Summary

There is widespread belief and some evidence to indicate that zinc can successfully treat tinnitus. Zinc deficiency is more likely to occur in the elderly . The primary objective of this study is to establish the effectiveness of zinc for the treatment of tinnitus in individuals 60 years of age and older. Subjects will be randomly assigned to either receive zinc daily or a placebo. After 4 months and a 1-month wash-out, the subjects will be crossed over to the other group.

Detailed description

There is widespread belief and some evidence to indicate that zinc can successfully treat tinnitus. Zinc deficiency is more likely to occur in the elderly . The primary objective of this study is to establish the effectiveness of zinc for the treatment of tinnitus in individuals 60 years of age and older. Subjects will be randomly assigned to either receive zinc daily or a placebo. After 4 months and a 1-month wash-out, the subjects will be crossed over to the other group. 116 patients were tested. Tinnitus loudness and the Tinnitus Handicap Questionnaire are the outcome measures.

Conditions

• Tinnitus

Interventions

Type	Name	Description
DRUG	Zinc	Zinc taken once daily
DRUG	Placebo oral capsule	Placebo capsules taken once daily

Timeline

• Start date: 2008-01-01
• Primary completion: 2011-12-01
• Completion: 2011-12-01
• First posted: 2008-05-23
• Last updated: 2017-12-13
• Results posted: 2017-12-13

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study