NCT00678756

Investigation of Antipsoriatic Effects of UVB-induced Synthesis of 1alpha, 25-Dihydroxyvitamin D3 (1alpha, 25(OH)2D3, Calcitriol)in Keratinocytes of Psoriatic Skin, Using Cytochrom-P(CYP)Inhibitor Ketokonazol

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 12 (estimated)
• Sponsor: Technische Universität Dresden · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Exploration of antipsoriatic effects of UVB-therapy +/- CYP-inhibitor Ketokonazol on affected psoriatic skin

Conditions

• Psoriasis Vulgaris

Interventions

Type	Name	Description
DRUG	Ketokonazol 2% cream	twice a day at 2 times,2 out of 5 areas have to be treated for 4 weeks/7 days a week
RADIATION	UVB-radiation 311nm	3 out of 5 areas are radiated for 4 weeks every MO/DI/DO/FR starting MED orientated, intensified everytime 0,03 J/qcm

Timeline

• Start date: 2008-03-01
• Primary completion: 2009-10-01
• Completion: 2009-12-01
• First posted: 2008-05-16
• Last updated: 2010-06-08

Locations

1 site across 1 country: Germany