NCT00675480

Thrombectomy in Acute Myocardial Infarction

Aspiration Thrombectomy as an Adjunctive Therapy to Primary Angioplasty in Patients With ST Segment Elevation Myocardial Infarction

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 140 (estimated)
• Sponsor: National Institute of Cardiology, Warsaw, Poland · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to determine whether thrombus removal with aspiration thrombectomy for acute myocardial infarction reduces the infarct size.

Detailed description

Acute myocardial infarction is caused by an abrupt occlusion of coronary vessel or severe reduction of coronary flow. It has been shown that the reperfusion therapy significantly improves the clinical outcome. Currently the optimal strategy is the primary angioplasty with stent implantation. The treatment is recommended by AHA/ACC and ESC if can be performed within 90 minutes from the first medical contact. However there is still a certain percentage of procedure failure. To further improve the outcome new techniques and devices are tested . Aspiration thrombectomy may facilitate the reperfusion by reducing thrombus burden. The aim of the study is to assess if adjunctive thrombectomy may improve clinical outcome in patients with an acute ST segment elevation myocardial infarction.

Conditions

• Acute Myocardial Infarction

Interventions

Type	Name	Description
PROCEDURE	Thrombectomy	Aspiration Thrombectomy prior to stent implantation in patients with ST segment elevation myocardial infarction
PROCEDURE	Primary angioplasty	Standard primary angioplasty with stent implantation

Timeline

• Start date: 2004-11-01
• Primary completion: 2008-09-01
• Completion: 2008-09-01
• First posted: 2008-05-09
• Last updated: 2009-01-29

Locations

1 site across 1 country: Poland