Clinical Trials Directory

Trials / Completed

CompletedNCT00673842

Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction

Risk Estimation Following Infarction Noninvasive Evaluation - ICD Efficacy

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
700 (estimated)
Sponsor
University of Calgary · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack, have abnormal test results from a 24 hour heart monitor, and who have low normal heart function.

Detailed description

The REFINE ICD trial will assess whether prophylactic ICD therapy, guided by non-invasive risk assessment tools, reduces mortality in MI survivors with better-preserved LV function.

Conditions

Interventions

TypeNameDescription
DEVICEImplantable Cardioverter Defibrillator + Usual CareAny Medtronic approved single chamber or dual chamber implantable cardioverter defibrillator (ICD)
OTHERUsual careUsual post-MI care

Timeline

Start date
2011-04-18
Primary completion
2024-10-31
Completion
2024-10-31
First posted
2008-05-07
Last updated
2025-05-30

Locations

79 sites across 15 countries: United States, Belgium, Canada, Finland, France, Germany, Hungary, Italy, Norway, Saudi Arabia, Slovakia, South Africa, Spain, Sweden, United Kingdom

Source: ClinicalTrials.gov record NCT00673842. Inclusion in this directory is not an endorsement.