Clinical Trials Directory

Trials / Completed

CompletedNCT00672477

Study Evaluating Subcutaneous Methylnaltrexone For Treatment Of Opioid-Induced Constipation In Patients With Advanced Illness

A Randomized, Double-Blind, Placebo-Controlled Study Of A Fixed Dose Of Subcutaneous Methylnaltrexone In Adults With Advanced Illness And Opioid-Induced Constipation: Efficacy, Safety, And Additional Health Outcomes

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
237 (actual)
Sponsor
Bausch Health Americas, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study will evaluate the safety and efficacy of methylnaltrexone administered as subcutaneous injections in subjects who have opioid-induced constipation and an advanced illness. The hypothesis is that methylnaltrexone will be safe and effective in relieving opioid-induced constipation in these subjects.

Conditions

Interventions

TypeNameDescription
DRUGMethylnaltrexone
DRUGPlacebo

Timeline

Start date
2008-06-01
Primary completion
2013-02-01
Completion
2013-02-01
First posted
2008-05-06
Last updated
2018-03-08
Results posted
2018-03-08

Locations

60 sites across 12 countries: United States, Australia, Belgium, Brazil, Canada, France, Germany, Italy, Mexico, Spain, Sweden, United Kingdom

Source: ClinicalTrials.gov record NCT00672477. Inclusion in this directory is not an endorsement.