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UnknownNCT00672269

Study Investigating MEN1 and SDHD in Familial Carcinoid Tumors

A Pilot Study to Investigate Germ-Line MEN1 and SDHD Gene Mutation in Familial Cases of Carcinoid Cancer

Status
Unknown
Phase
Study type
Observational
Enrollment
25 (estimated)
Sponsor
Rutgers University · Academic / Other
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

There is a high incidence among the first degree relatives of the carcinoid patients, indicating the involvement of genetic components in its initiation and pathogenesis.

Detailed description

This proposed pilot study will conduct detailed interviews into the medical, environmental, and family histories and to collect blood specimen to obtain DNA. The Blood specimen and DNA will be processed by the Rutgers University Cell and DNA Repository (RUCDR) to rule out Familial Multiple Endocrine Neoplasia (MEN 1), and succinate dehydrogenase complex, subunit D (SDHD), gene inactivation thought to be associated with different types of carcinoid cancer.

Conditions

Timeline

Start date
2008-04-01
Primary completion
2009-04-01
Completion
2010-06-01
First posted
2008-05-06
Last updated
2009-02-04

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00672269. Inclusion in this directory is not an endorsement.

Study Investigating MEN1 and SDHD in Familial Carcinoid Tumors (NCT00672269) · Clinical Trials Directory