NCT00670787

Combination Pill of Losartan Potassium and Hydrochlorothiazide for Improvement of Medication Compliance Trial

A Randomized Trial to Establish the Effects of Combination Pill of Losartan Potassium and Hydrochlorothiazide on Medication Compliance Among Patients With High Blood Pressure.

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 207 (actual)
• Sponsor: Kyushu University · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to determine whether combination pill of losartan potassium and hydrochlorothiazide will improve medication compliance among patients with high blood pressure.

Detailed description

Despite clear evidence that blood pressure lowering treatment is beneficial for reduction of cardiovascular disease, blood pressure levels are not adequately controlled in many hypertensive patients. More intensive blood pressure lowering treatment is required to achieve maximum reduction of cardiovascular disease. Combination pills of blood pressure lowering drugs could be a safe and effective strategy to achieve blood pressure target but there is no randomized evidence that established the beneficial effects of combination pills of blood pressure lowering drugs. The purpose of the study is to determine whether combination pill of losartan potassium and hydrochlorothiazide will improve medication compliance among patients with high blood pressure.

Conditions

• Hypertension

Interventions

Type	Name	Description
DRUG	Combination pill of losartan and hydrochlorothiazide	Combination pill of losartan potassium 50mg and hydrochlorothiazide 12.5mg in the morning

Timeline

• Start date: 2008-06-01
• Primary completion: 2010-11-01
• Completion: 2011-02-01
• First posted: 2008-05-02
• Last updated: 2011-03-07

Locations

1 site across 1 country: Japan