Clinical Trials Directory

Trials / Completed

CompletedNCT00666783

An Efficacy and Safety Study of Palonosetron in Preventing Chemotherapy-Induced Nausea and Vomiting (CINV) in the Chinese Cancer Patients

A Phase II, Multicenter,Double-Blind, Randomized Trial of Palonosetron Compared With Granisetron in Preventing Highly Emetogenic Chemotherapy-Induced Nausea and Vomiting in the Chinese Cancer Patients

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
208 (actual)
Sponsor
Xijing Hospital · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

This clinical study was designed to demonstrate that a single, intravenous dose of palonosetron 0.25 mg was not inferior to granisetron 3 mg in preventing acute and delayed CINV and was also well tolerated in the Chinese cancer patients.

Conditions

Interventions

TypeNameDescription
DRUGpalonosetronreceive a single, intravenous dose of palonosetron 0.25 mg, 30 minutes before receiving highly emetogenic chemotherapy.
DRUGGranisetronreceive a single, intravenous dose of granisetron 3 mg, 30 minutes before chemotherapy.

Timeline

First posted
2008-04-25
Last updated
2008-04-25

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT00666783. Inclusion in this directory is not an endorsement.