Trials / Completed
CompletedNCT00663494
Matrix Metalloproteinase (MMP) in Heart Failure
MMP is Produced in Failing Hearts
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 22 (estimated)
- Sponsor
- Tottori University Hospital · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- —
Summary
The purpose of this study is to evaluate the production of MMP in failing hearts.
Detailed description
Myocardial fibrosis is observed in failing hearts and parallel to the progression of chronic heart failure (CHF) and myocardial remodeling. Matrix metalloproteinases (MMPs) are considered markers of fibrosis. Recently, circulating MMPs can be measured and are elevated in patients with CHF. However, MMPs it is still unclear whether MMPs are produced in failing hearts. Thus, the purpose of this study is to evaluate the production of MMP in failing hearts.
Conditions
Timeline
- Start date
- 2003-02-01
- Completion
- 2006-07-01
- First posted
- 2008-04-22
- Last updated
- 2011-07-21
Source: ClinicalTrials.gov record NCT00663494. Inclusion in this directory is not an endorsement.