Trials / Terminated
TerminatedNCT00661011
Lobectomy and Mediastinal Radiochemotherapy in Unresectable Stage III Non-Small Cell Lung Cancer Responding to Induction Chemotherapy
A Phase II Study Assessing the Curative Effect of the Combination of Lobectomy Followed by Mediastinal Concomitant Radiochemotherapy in Patients With Locally Advanced Unresectable Stage III Non-small Cell Lung Cancer Responding to Induction Chemotherapy
- Status
- Terminated
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 75 (actual)
- Sponsor
- European Lung Cancer Working Party · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine if radical radiochemotherapy on the mediastinum after lobectomy can be associated with significant long term survival in patients with initially unresectable stage III NSCLC responding to induction chemotherapy but in which the residual disease is too large to be treated by radiotherapy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Lobectomy followed by concomitant mediastinal chemoradiotherapy | Lobectomy Radiotherapy 66 Gy in 2 Gy/ fraction, 5 fractions/wk Chemotherapy Cisplatin 60 mg/m² on days 1 and 22 and Vinorelbine 15 mg/m² on days 1, 8, 22 and 29 |
Timeline
- Start date
- 2007-01-01
- Primary completion
- 2013-12-01
- Completion
- 2014-06-01
- First posted
- 2008-04-18
- Last updated
- 2015-02-12
Locations
12 sites across 3 countries: Belgium, Greece, Spain
Source: ClinicalTrials.gov record NCT00661011. Inclusion in this directory is not an endorsement.