NCT00660933

Intravenous Iron Versus Oral Iron for Severe Postpartum Anemia

Intravenous Iron Versus Oral Iron for Severe Postpartum Anemia Randomized Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Hospital Clinic of Barcelona · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to compare the effect of intravenous versus oral iron in women with severe postpartum anemia.

Detailed description

Postpartum anemia is commonly defined as hemoglobin levels less than 8.5 g/dl and it is usually treated with oral iron supplements. Blood transfusion is reserved to women with hemoglobin levels \< 6 g/dl and/or clinical symptoms of anemia. Without treatment, the restoration of blood parameters in postpartum anemia can take approximately one month (hemoglobin levels increase to 2.8 g/dl in 30 days). Several reports have demonstrated the efficacy of intravenous iron in severe anemia in non-obstetric pathologies. However, the clinical effect of intravenous iron in patients with postpartum hemoglobin levels ranging from 6.0 to 8.0 g/dl has been not reported. There has not been evaluated its capacity to restore hemoglobin levels and to minimize clinical side-effects of anemia (sickness, weariness, depression, anxiety).

Conditions

• Anemia
• Puerperal Disorders

Interventions

Type	Name	Description
DRUG	Iron sucrose	Iron sucrose 200 mg/day iv, (20 mg/ml) + 200 cc de NaCl 0,9%/day in 60 minutes per 2 days.
DRUG	NaCl	NaCl 0,9% 200 ml /day iv in 60 minutes per 2 days

Timeline

• Start date: 2005-09-01
• Primary completion: 2007-09-01
• Completion: 2007-09-01
• First posted: 2008-04-17
• Last updated: 2016-03-08

Locations

1 site across 1 country: Spain