Trials / Unknown
UnknownNCT00660465
Exploring the Relationship Between Varying CO2 Levels and the Regional BOLD Signal, by Using Breathing Exercises
Exploring the Relationship Between Varying CO2 Levels and the Regional BOLD Signal, by Using Breathing Exercises .
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 6 (estimated)
- Sponsor
- Soroka University Medical Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to explore how arterial PaCO2 effect regional Blood Oxygen Level Dependent (BOLD) signal, and indirectly the brain regional O2 level .
Detailed description
Among many parameters effecting cerebral blood flow(CBF), partial pressure of CO2 (PaCO2) in arterial blood has a significant effect. A small increase in arterial PaCO2 level will cause a significant increase of CBF , followed by increase of O2 level . The main objective is to explore the effect of arterial PaCO2 level on regional CBF and brain O2 level, by using breathing exercises to modulate arterial PaCO2. The regional Blood Oxygen Level Dependent (BOLD) signal produced by MRI , will indicate the regional O2 level.
Conditions
Timeline
- Start date
- 2008-05-01
- First posted
- 2008-04-17
- Last updated
- 2014-11-11
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT00660465. Inclusion in this directory is not an endorsement.