NCT00659542

Glubran Mesh Fixation in Lichtenstein Hernioplasty

Randomized Study of Mesh Fixation With Absorbable Sutures or Glubran Tissue Sealant in Lichtenstein Hernioplasty

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Kuopio University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to investigate whether chronic postoperative pain is less frequent and quality of life better when inguinal mesh is fixed by using tissue glue compared to conventional sutures in inguinal hernioplasty.

Detailed description

Repair of inguinal hernia in one of the most frequently performed surgical operation in western world. The technique of choice is currently to support inguinal tissues by using polypropylene mesh. Chronic postoperative pain and discomfort occur in 25-30% of patients after inguinal hernioplasty. Pain might be related to mesh fixation by sutures. This randomized study investigates whether mesh fixation by tissue glue (cyanoacrylate) is better than sutures. The patients are followed 1 year postoperatively. Pain, quality of life, operative parameters (time, cost) and recurrences are reported.

Conditions

• Inguinal Hernia

Interventions

Type	Name	Description
PROCEDURE	cyanoacrylate glue	1 ml glue

Timeline

• Start date: 2007-10-01
• Primary completion: 2008-12-01
• Completion: 2009-12-01
• First posted: 2008-04-16
• Last updated: 2010-03-11

Locations

1 site across 1 country: Finland