NCT00659308

Amniotic Membrane and Anterior Stromal Puncture to the Treatment of Symptomatic Bullous Keratopathy

Amniotic Membrane and Anterior Stromal Puncture: a Comparative Study in the Treatment of Symptomatic Bullous Keratopathy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 38 (actual)
• Sponsor: Federal University of São Paulo · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether amniotic membrane transplantation is as effective as anterior stromal puncture in the relief of symptomatic bullous keratopathy.

Detailed description

Patients with symptomatic bullous keratopathy were randomized in 2 groups and submitted to amniotic membrane transplantation or anterior stromal puncture. The follow up was made with 1, 3, 6 and 12 months. Evaluation included complete ophthalmologic exam, esthesiometry, pachymetry, impression cytology and evaluation of pain.

Conditions

• Bullous Keratopathy

Interventions

Type	Name	Description
PROCEDURE	amniotic membrane transplantation	patients are submitted to amniotic membrane transplantation
PROCEDURE	anterior stromal puncture	the other group is submitted to anterior stromal puncture

Timeline

• Start date: 2005-06-01
• Primary completion: 2005-07-01
• Completion: 2007-06-01
• First posted: 2008-04-16
• Last updated: 2008-04-16

Locations

1 site across 1 country: Brazil