NCT00657124

Effect of Preoperative Supplementation in Insulin Resistance

Preoperative Oral Supplementation of Carbohydrate and Branched-Chain Amino Acids-Enriched Nutrient Improves Insulin Resistance in Patients With Hepatectomy; Prospective Randomized Clinical Trial by Using Artificial Pancreas

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 26 (actual)
• Sponsor: Kochi University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

To elucidate the effect of preoperative supplementation of carbohydrate and branched-chain amino acids on postoperative insulin resistance in patients undergoing hepatic resection, we set a randomized trial.

Detailed description

Twenty-six patients with hepatectomy due to a live tumor were prospectively randomized to receive a preoperative supplementation with carbohydrate and branched-chain amino acids-enriched nutrient or not.

Conditions

• Liver Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Aminolevan EN	The present study used carbohydrate and BCAA-enriched soft-powder nutrient-mixture for preoperative supplementation. Supplementation with Aminolevan EN (100 g per day) started at two weeks prior to the surgery under the careful monitoring of compliance.
DIETARY_SUPPLEMENT	Placebo	placebo

Timeline

• Start date: 2007-04-01
• Primary completion: 2007-12-01
• Completion: 2007-12-01
• First posted: 2008-04-14
• Last updated: 2008-04-14

Locations

1 site across 1 country: Japan