NCT00656487

Clinical and Neurobiological Effects of Cannabis Dependence in Young Adults

Translational Center on the Clinical Neurobiology of Cannabis Addiction

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: The Scripps Research Institute · Academic / Other
• Sex: All
• Age: 21 Years – 30 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to find out more about cognitive functioning in people who are cannabis dependent, relative to people who do not use cannabis, and how their brains process information after one month of not using cannabis. An additional goal is to characterize the severity of cannabis dependence using precipitated and naturalistic withdrawal with a double blind, placebo controlled, single administration of rimonabant. Research assessments occur bi-weekly throughout this 28 day study.

Conditions

• Cannabis Dependence
• Cannabis Withdrawal

Interventions

Type	Name	Description
DRUG	rimonabant	double blind, placebo controlled, single 90 mg dose
DRUG	placebo	matched placebo

Timeline

• Start date: 2008-04-30
• Primary completion: 2010-12-28
• Completion: 2011-01-06
• First posted: 2008-04-11
• Last updated: 2017-06-19
• Results posted: 2017-05-15

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study