NCT00652678

Predictive Blood Tests for Severe Radiation Reactions in Breast Cancer Patients

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 38 (actual)
• Sponsor: State University of New York - Upstate Medical University · Academic / Other
• Sex: Female
• Age: 48 Years
• Healthy volunteers: Not accepted

Summary

Some patients who undergo breast cancer treatment with lumpectomy followed by radiation therapy develop significant late skin and soft tissue changes, resulting in a poor cosmetic outcome. The goal of this study is to try to predict severe tissue reactions by using a combination of three of the latest blood tests, one of which we have developed ourselves.

Detailed description

Three tubes of blood will be drawn from each subject. Two members of the study team will also independently assess each subject for the degree to which various radiation-induced soft tissue changes are evident. Subjects will be put into three groups according to the severity of the soft tissue changes which are noted, and the results of the blood tests for members of each group will be analyzed to determine whether a correlation with cosmetic outcomes can be determined. If the results are promising, they will be studied further and used as the basis for future prospective clinical trials.

Conditions

• Abnormalities, Radiation-Induced

Timeline

• Start date: 2006-08-01
• Primary completion: 2012-08-01
• Completion: 2012-08-01
• First posted: 2008-04-04
• Last updated: 2021-10-22

Locations

1 site across 1 country: United States