NCT00652015

Molecular and Cellular Mechanisms of the In-stent-thrombosis

Molecular and Cellular Mechanisms of the In-stent-thrombosis. Is it Possible to Predict a In-stent-thrombosis Using Biomarkers?

• Status: Withdrawn
• Phase: —
• Study type: Observational
• Enrollment: 0 (actual)
• Sponsor: RWTH Aachen University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

In-Stent-Thrombosis is a rare but serious complication after implantation of stents during PTCA.

Detailed description

In this prospective, open, not-randomized, controlled single-center pilot study 80 patients having had an in-stent-thrombosis (40 sub-acute thromboses (SAT), 40 late thromboses (LT)) and a control group of 80 patients having not developed a thrombosis will be compared. The aim of this study is the establishment of diagnostic markers vor prediction of SAT (detection of CD39- and CD73-activity, respectively)and of LT (EPC-number and function, respectively) correspondingly aiming at the early identification of patients with high risk for developing an in-stent-thrombosis.

Conditions

• Patients With SAT or LT After Stent Implantation (PCI)

Timeline

• Start date: 2008-05-01
• Primary completion: 2010-05-01
• Completion: 2010-05-01
• First posted: 2008-04-03
• Last updated: 2015-09-23

Locations

1 site across 1 country: Germany