NCT00650715

Effects of Whole-Body Vibration Exercise on Serum IGF-1 in Fibromyalgia

Effect of Acute and Chronic Whole-Body Vibration Exercise on Serum Insulin-Like Growth Factor-1 Levels in Women With Fibromyalgia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Institut Nacional d'Educacio Fisica de Catalunya · Academic / Other
• Sex: Female
• Age: 35 Years – 69 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study was to investigate the acute and chronic effect of whole-body vibration exercise on serum insulin-like growth factor-1 levels in women with fibromyalgia (FM). It was hypothesized that women with FM would exhibit an increase in IGF-1 following both acute and chronic WBV. Twenty-four women with FM were randomized into two groups: Vibration Group (VG) and Control Group (CG). The VG underwent a protocol with WBV exercise twice a week for a total of six weeks, whereas the CG performed the same protocol without vibratory stimulus. Both groups continued with their usual pharmacological treatment. Serum IGF-1 levels were determined using Enzyme-Linked Immunosorbent Assay (ELISA). To test the effect of chronic WBV, serum IGF-1 measurements were taken at baseline and at weeks 1,3, and 6 of intervention. To test the effect of acute WBV, within week 1, serum IGF-1 measurements were taken before and immediately following a session of WBV.

Conditions

• Fibromyalgia
• Hormonal Responses to Exercise in Patients With Fibromyalgia.

Interventions

Type	Name	Description
DEVICE	Vibratory platform, PowerPlate®, Badhoevendorp, Netherlands	Six exercises (static and dynamic tasks) while standing on a Whole-body vibration platform. The six exercises (30 seconds each) were repeated six times with a recovery of 3 minutes in between. The Whole-body vibration intensity was kept constant at 30 Hz of frequency and 2 mm of amplitude.
DEVICE	Placebo Whole-body vibration exercise	Six exercises (static and dynamic tasks) while standing on a Whole-body vibration platform. The six exercises (30 seconds each) were repeated six times with a recovery of 3 minutes in between. All exercises were performed without the influence of a vibratory stimulus.

Timeline

• Start date: 2004-12-01
• Primary completion: 2005-01-01
• Completion: 2005-01-01
• First posted: 2008-04-02
• Last updated: 2008-04-02

Locations

1 site across 1 country: Spain