Trials / Completed
CompletedNCT00648310
Topical Oestrogens and Antimuscarinics In The Treatment Of Detrusor Overactivity
Is There A Synergic Effect Of Topical Oestrogens When Associated To Antimuscarinics In The Treatment Of Symptomatic Detrusor Overactivity
- Status
- Completed
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Università degli Studi dell'Insubria · Academic / Other
- Sex
- Female
- Age
- —
- Healthy volunteers
- Not accepted
Summary
Despite the great number of reports about the efficacy of oestrogens or antimuscarinics on OAB symptoms, so far no author has tried to investigate whether the concomitant administration of these two drugs, acting on two different pathophysiological mechanisms, could have a synergic effect reducing the rate of non-responders to treatment.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Tolterodine 4 mg | |
| DRUG | arm 2: Tolterodine 4 mg + local oestrogens once daily for 12 weeks |
Timeline
- Start date
- 2004-01-01
- Completion
- 2007-12-01
- First posted
- 2008-04-01
- Last updated
- 2008-04-01
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT00648310. Inclusion in this directory is not an endorsement.