NCT00644657

The Effect of Clopidogrel on Coated-Platelets in Patients Undergoing Cardiac Catheterization

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 27 (actual)
• Sponsor: University of Oklahoma · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

This study will explore the effect of clopidogrel on coated-platelets in patients who are given a loading dose before diagnostic catheterization or percutaneous coronary intervention. We hypothesis that clopidogrel will reduce the percentage of platelets that are coated and therefore more hypercoagulable.

Detailed description

Platelet activity will be determined by light transmission aggregometry at baseline, after a 300 mg dose of clopidogrel and after the catheterization and/or angioplasty procedure. The change in the percentage of platelets that are coated platelets will be determined.

Conditions

• Coronary Artery Disease
• Chest Pain

Interventions

Type	Name	Description
DRUG	Clopidogrel	All subjects will receive a 300 mg loading dose

Timeline

• Start date: 2007-03-01
• Primary completion: 2008-09-01
• Completion: 2008-09-01
• First posted: 2008-03-27
• Last updated: 2011-10-07
• Results posted: 2011-10-07

Locations

1 site across 1 country: United States