Clinical Trials Directory

Trials / Completed

CompletedNCT00644553

Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial Sinusitis

A Phase IIIB/IV Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets vs. Amoxicillin-Clavulanate for the Treatment of Subjects With Acute Bacterial Sinusitis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
437 (actual)
Sponsor
Abbott · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

To compare the safety/tolerability and efficacy of a 14-day course of clarithromycin extended-release tablets (2 x 500 mg QD) with that of a 14-day course of amoxicillin-clavulanate tablets (875/125 mg BID) for the treatment of ambulatory subjects with Acute Bacterial Sinusitis (ABS).

Conditions

Interventions

TypeNameDescription
DRUGClarithromycinClarithromycin Extended-Release 500 mg tablet (2 tablets QD)
DRUGAmoxicillinAmoxicillin-clavulanate 875/125 mg tablet (1 tablet BID)

Timeline

Start date
2003-05-01
Primary completion
2004-03-01
First posted
2008-03-27
Last updated
2008-03-27

Locations

53 sites across 9 countries: United States, Canada, Greece, Hungary, Italy, Lithuania, Poland, Romania, Spain

Source: ClinicalTrials.gov record NCT00644553. Inclusion in this directory is not an endorsement.