NCT00642070

Host Response to Urinary Tract Infection in Women

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 326 (actual)
• Sponsor: University of Washington · Academic / Other
• Sex: Female
• Age: 18 Years – 49 Years
• Healthy volunteers: Accepted

Summary

This study is being done to identify those elements of the immune response that may predispose a woman to recurrent urinary tract infection. We suspect that lesser effectiveness of certain components of the host response will lead to recurrent urinary tract infection. We will also evaluate the role that the bladder reservoir may play in recurrent urinary tract infection.

Detailed description

Procedures subjects will undergo once they have read and signed the consent are: Questions about their medical and sexual history and current symptoms of urinary tract infection. They will be asked to provide a clean catch urine sample. We will collect periurethral, vaginal and rectal swabs. Blood will collected. They will be given a diary to take home and record all episodes of sexual intercourse, contraceptive use, vaginal and urinary symptoms and medication use. They will be given standard treatment for the current urinary tract infection. Follow-up visits will be scheduled 2 weeks,one month,two month and three month after initial visit.

Conditions

• Urinary Tract Infection

Timeline

• Start date: 2008-02-01
• Primary completion: 2012-07-01
• Completion: 2012-07-01
• First posted: 2008-03-24
• Last updated: 2014-06-05

Locations

1 site across 1 country: United States