NCT00641784

Tocolytics Trial: Intravenous (IV) Magnesium Versus Oral Nifedpine in Fetal Fibronectin (FFN) Postive Population

A Randomized Trial of Oral Nifedipine Versus Intravenous Magnesium Sulfate in the Acute Management of Preterm Labor in Women With Singleton Gestations, Intact Fetal Membranes, and Positive Vaginal Fetal Fibronectin

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: MemorialCare · Academic / Other
• Sex: Female
• Age: 18 Years – 55 Years
• Healthy volunteers: Not accepted

Summary

In women with singleton gestations, to contemporarily assess the efficacy of oral nifedipine versus intravenous magnesium sulfate in the acute management of preterm labor in terms of defined early and late neonatal measures

Conditions

• Labor, Premature

Interventions

Type	Name	Description
DRUG	Magnesium	Intravenous Magnesium 6 gram load, 3 grams/hr
DRUG	Nifedlipine	Oral Nifedpine 10 mgs q 20 min to effect (max 40mgs)...then 20 mgs q 4hrs

Timeline

• Start date: 2008-03-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2008-03-24
• Last updated: 2009-09-18

Locations

1 site across 1 country: United States