NCT00641433

Topical Collagen-Silver Versus Standard Care Following Removal of Ingrown Nails

Topical Collagen-Silver Versus Standard Care Following Phenol Ablation of Ingrown Nails: A Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Rosalind Franklin University of Medicine and Science · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study's purpose is to prospectively determine whether topical therapy with an oxidized regenerated cellulose collagen-silver compound is more effective than the current standard of topical antibiotic therapy for care following the removal of an ingrown toenail. Eighty adult patients with ingrown toenails will be recruited. Each patient will randomly be assigned to apply either topical silver sulfadiazine cream (standard antibiotic) or the novel collagen-silver compound to their nail bed daily, following removal of the ingrown portion of nail. Patients will return for follow up visits weekly, until healing has occurred or twelve weeks have passed. Healing will be defined as resolution of drainage and inflammatory changes surrounding the nail border.

Conditions

• Ingrown Nail

Interventions

Type	Name	Description
DEVICE	oxidized regenerated cellulose collagen-silver	Wound dressed daily with oxidized regenerated cellulose collagen-silver matrix.
DRUG	topical silver sulfadiazine cream	Cream will be applied to nailbed daily and dressed with a bandage until healing occurs.

Timeline

• Start date: 2005-11-01
• Primary completion: 2008-05-01
• Completion: 2008-05-01
• First posted: 2008-03-24
• Last updated: 2008-03-24

Locations

2 sites across 1 country: United States