NCT00639899

The Effect of Spermatic Vein Embolization on Prostatic Hypertrophy

Selective Retrograde Venography and Sclerotherapy of Internal Spermatic Veins and Associated Venous Bypasses and Retro-Peritoneal Collateral in Patients With Varicocele and Hypertrophy of Prostate

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 35 (actual)
• Sponsor: Maaynei Hayesha Medical Center · Academic / Other
• Sex: Male
• Age: 45 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

In varicocele the venous pressure in the prostatic bed is increased .This may result in raised hydrostatic pressure which in turn may stimulate prostatic hypertrophy. Restoring normal venous drainage is expected to lower hydrostatic pressure followed by inhibition of prostatic growth and possibly leading regression in prostatic dimensions.

Detailed description

35 male patients, aged 45 years or older, with documented benign prostatic hypertrophy (BPH)and varicocele as visualized by ultrasound and/or termography examination will be enrolled. Each patient will undergo a full urologic examination to exclude possible malignancy as well as a thorough medical examination to establish eligibility for treatment. In all selected patients the varicocele will be obliterated by means of embolization of the spermatic veins. The patients will be followed every three months by abdominal ultrasound as well as by serial PSA for a period of 6-12 months.

Conditions

• Varicocele

Interventions

Type	Name	Description
PROCEDURE	Sclerotherapy	Super-selective retrograde venography and sclerotherapy of internal spermatic veins and associated venous bypasses and retro-peritoneal collateral

Timeline

• Start date: 2007-09-01
• Primary completion: 2008-03-01
• Completion: 2008-03-01
• First posted: 2008-03-20
• Last updated: 2008-03-20

Locations

1 site across 1 country: Israel