Clinical Trials Directory

Trials / Completed

CompletedNCT00638989

A Study to Assess Bioavailability and Pharmacokinetics of CAT- 354

An Open-Label, Parallel-Group, Bioavailability Study to Assess the Pharmacokinetics of CAT-354 Following Subcutaneous and Intravenous Administration

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
30 (actual)
Sponsor
MedImmune LLC · Industry
Sex
Male
Age
19 Years – 55 Years
Healthy volunteers
Accepted

Summary

To compare bioavailability and pharmacokinetics of CAT-354 following subcutaneous administration compared with intravenous administration.

Detailed description

To compare the bioavailability and pharmacokinetics of CAT-354 following subcutaneous administration of 150 milligram (mg) and 300 mg compared with 150 mg given intravenously.

Conditions

Interventions

TypeNameDescription
BIOLOGICALCAT-354 150 mg (intravenous)A single dose of CAT-354 150 milligram (mg) intravenous infusion over 30 minutes on Day 0.
BIOLOGICALCAT-354 150 mg (subcutaneous)A single dose of CAT-354 150 mg injection subcutaneously on Day 0.
BIOLOGICALCAT-354 300 mg (subcutaneous)A single dose of CAT-354 300 mg injection subcutaneously on Day 0.

Timeline

Start date
2008-04-11
Primary completion
2008-06-07
Completion
2008-06-07
First posted
2008-03-19
Last updated
2017-05-04
Results posted
2017-05-04

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00638989. Inclusion in this directory is not an endorsement.