NCT00638326

Doubling the Maintenance Dose of Clopidogrel in Patients With High On-Clopidogrel Platelet Reactivity

150 mg Maintenance Dose of Clopidogrel in Patients With High On-Clopidogrel Platelet Reactivity After Elective Percutaneous Coronary Intervention

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 500 (estimated)
• Sponsor: University of Pecs · Academic / Other
• Sex: All
• Age: 35 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to determine whether administration of 150 mg clopidogrel is effective in reducing the one-year incidence of thromboischemic events in patients with high on-clopidogrel platelet reactivity compared to 75 mg clopidogrel after elective percutaneous coronary intervention.

Conditions

• Stable Angina Pectoris
• Ad Hoc Percutaneous Coronary Intervention

Interventions

Type	Name	Description
DRUG	clopidogrel	150 mg maintenance dose (2 capsules of 75 mg clopidogrel) for 28 days followed by standard 75 mg clopidogrel for one year
DRUG	clopidogrel plus placebo	75 mg maintenance dose (one capsule of 75 mg clopidogrel and one capsule placebo) for 28 days followed by standard 75 mg clopidogrel for one year

Timeline

• Start date: 2008-03-01
• Primary completion: 2009-09-01
• Completion: 2010-03-01
• First posted: 2008-03-19
• Last updated: 2010-03-23

Locations

1 site across 1 country: Hungary