NCT00636389

Molecule Removal and Ease of Use: A Comparison of Two Different Dialyzers

Urea, Phosphate and b2-Microglobulin Removal and Ease of Use: Comparing the Polyflux HD-C4 With the Polyflux 210H

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Vantive Health LLC · Industry
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The Polyflux HD-C4 (Gambro Renal Products) is a new dialyzer based on the existing Polyflux H membrane and dialyzer technology, but which achieves a performance comparable to Polyflux 210H in a significantly smaller device. The objectives of this study are: 1. To compare and contrast small and large molecule removal by the Polyflux HD-C4 and Polyflux 210H dialyzers under conditions of routine hemodialysis; and, 2. To compare and contrast the ease of use of the Polyflux HD-C4 dialyzer with that of the Polyflux 210H under conditions of routine clinical use for hemodialysis.

Conditions

• Chronic Kidney Disease

Interventions

Type	Name	Description
DEVICE	Polyflux 210H dialyzer	Three consecutive treatments with the Polyflux 210H dialyzer. All study treatments will be performed in the standard hemodialysis mode.
DEVICE	Polyflux HD-C4	Three consecutive treatments with the Polyflux HD-C4 dialyzer. All study treatments will be performed in the standard hemodialysis mode.

Timeline

• Start date: 2008-02-01
• Primary completion: 2008-12-01
• Completion: 2009-03-01
• First posted: 2008-03-14
• Last updated: 2025-07-14
• Results posted: 2011-08-11

Locations

1 site across 1 country: United States