Clinical Trials Directory

Trials / Completed

CompletedNCT00634959

Effects Of Food And Dose Regimen On The Antiviral Effects Of Maraviroc (UK-427,857) In Patients With Human Immunodeficiency Virus

An Investigation Into The Effects Of Food And Dose Regimen On Viral Load Response In HIV Infected Patients On Short-Term Monotherapy With UK-427,857 (Maraviroc)

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
37 (actual)
Sponsor
ViiV Healthcare · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Not accepted

Summary

To investigate the effects of food and dose regimen on the antiviral effects of Maraviroc (UK-427,857) in patients with human immunodeficiency virus (HIV)

Conditions

Interventions

TypeNameDescription
DRUGMaraviroc (UK-427,857)150 mg oral tablet twice daily while fasted on Days 1-9 and on Day 10 (morning dose only)
DRUGMaraviroc (UK-427,857)100 mg oral tablet once daily while fasted on Days 1-10
DRUGMaraviroc (UK-427,857)300 mg oral tablet once daily while fasted on Days 1-10
DRUGMaraviroc (UK-427,857)150 mg oral tablet twice daily with food on Days 1-9 and on Day 10 (morning dose only)
OTHERPlaceboMatching placebo oral tablet on Days 1-10 (fed and fasted)

Timeline

Start date
2003-07-01
Completion
2003-12-01
First posted
2008-03-13
Last updated
2010-11-10

Locations

7 sites across 3 countries: United States, Germany, United Kingdom

Source: ClinicalTrials.gov record NCT00634959. Inclusion in this directory is not an endorsement.