NCT00633581

Efficacy of Vitamin C Injection on Fatigue in Workers After Work

Efficacy of High Dose Vitamin C Parenteral Supplement on Amelioration of Fatigue in Company Workers After Work: A Double-Blind, Randomized Controlled Trial

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: DongGuk University · Academic / Other
• Sex: All
• Age: 20 Years – 49 Years
• Healthy volunteers: Accepted

Summary

Fatigue is one of the most frequently observed symptoms for company workers, and oxidative stress is regarded as one of its cause. Vitamin C is a well-known antioxidant, and the investigators seek for evidence of the efficacy of high dose vitamin C parenteral supplement on fatigue symptoms of company workers after work.

Detailed description

Previous studies dealing with vitamin C were focusing on terminal cancer patients or those with chronic fatigue syndrome. Since used drug dosage and the ways of administering vitamin C were not identical, the results were not consistent throughout those studies. This study is aimed to evaluate the efficacy of high dose vitamin C with parenteral supplement on relieving fatigue for apparently healthy volunteers.

Conditions

• Fatigue

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Ascorbic acid (Vitamin C)	Single intravenous injection of vitamin C 10g(20ml) with 100ml of normal saline over 30 minutes
DIETARY_SUPPLEMENT	Normal saline	Single intravenous injection of 120ml of normal saline over 30 minutes

Timeline

• Start date: 2008-03-01
• Primary completion: 2008-05-01
• Completion: 2008-05-01
• First posted: 2008-03-12
• Last updated: 2009-04-10

Locations

1 site across 1 country: South Korea