Trials / Terminated
TerminatedNCT00633568
Randomised Study of Concomitant Radiochemotherapy in Non-small Cell Lung Cancer
A Phase III Randomised Study Comparing Concomitant Radiochemotherapy With Cisplatin and Docetaxel as Induction Versus Consolidation Treatment in Patients With Locally Advanced Unresectable Non-small Cell Lung Cancer.
- Status
- Terminated
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 125 (actual)
- Sponsor
- European Lung Cancer Working Party · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of the present trial is to assess if induction concurrent chemoradiotherapy followed by consolidation chemotherapy will improve survival in comparison with the same chemotherapy given as induction followed by consolidation concurrent chemoradiotherapy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Concomitant Radiochemotherapy - Radiotherapy 66 Gy, Cisplatin, and Docetaxel | Concurrent chemoradiotherapy: Radiotherapy 66 Gy in 2 Gy/fraction, 5 fractions/wk (6.5 weeks)with Cisplatin 20 mg/m²/week (6 times, beginning on day 1 of radiotherapy)and Docetaxel 20 mg/m²/week (6 times, beginning on day 1 of radiotherapy) Chemotherapy : Cisplatin 60 mg/m² and Docetaxel 75 mg/m² on day 1 |
| DRUG | Concomitant Chemoradiotherapy - Radiotherapy 66 Gy, Cisplatin, and Docetaxel | Concurrent chemoradiotherapy: Radiotherapy 66 Gy in 2 Gy/fraction, 5 fractions/wk (6.5 weeks)with Cisplatin 20 mg/m²/week (6 times, beginning on day 1 of radiotherapy)and Docetaxel 20 mg/m²/week (6 times, beginning on day 1 of radiotherapy) Chemotherapy : Cisplatin 60 mg/m² and Docetaxel 75 mg/m² on day 1 |
Timeline
- Start date
- 2007-01-01
- Primary completion
- 2014-12-01
- Completion
- 2015-02-01
- First posted
- 2008-03-12
- Last updated
- 2015-02-12
Locations
19 sites across 4 countries: Belgium, France, Greece, Spain
Source: ClinicalTrials.gov record NCT00633568. Inclusion in this directory is not an endorsement.