NCT00633308

Phosphorus and Calcium Removal During Long Hemodialysis Treatment Sessions

• Status: Withdrawn
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Indiana University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this sudy is to determined the effect of dialysate volume and treatment time on phosphate and calcium removal in stage V chronickidney disease patients treated by hemodialysis using the System One (NxStage Medical, Lawrence, MA)

Detailed description

Ten patients will be recruited from those routinely treated in-center or at home using the Systerm One at the clinical centers. Each patient will be studiesd on 4 separate occastions. Treatments under the following conditions will each be performed on each study patient, at least one week apart: 1. Treatment for 8 hrs uding 40L of dialysate 2. Treatment for 8 hrs using 60L of dialysate 3. Treatment for 5 hrs using 40L of dialysate 4. Treatment for 5 hrs using 60L of dialysate Blood samples will be collected and assayed for the concentrations of urea, phosphate, calcium, bicarbonate, beta-2-microglobulin and albumin using standard assays.

Conditions

• Kidney Failure

Interventions

Type	Name	Description
DEVICE	NxStage System One (NxStage Medical, Lawrence, MA)	Each patient will be studied on 4 separate occasions. The study sessions are longer than routine daily hemodialysis therapy using the System One.

Timeline

• Start date: 2008-03-01
• Primary completion: 2010-01-01
• Completion: 2011-02-01
• First posted: 2008-03-12
• Last updated: 2016-03-01